Researchers from the Mayo Clinic and their collaborators have released a new study identifying genetic markers that pinpoint which people may benefit most from administration of the drug acamprosate as treatment for alcoholism.<\/p>\n
While acamprosate is not a new AUD treatment, past studies have shown that the drug is only effective for a certain percentage of patients.<\/p>\n
The study, published in Translational Psychiatry<\/em> (October 7, 2014), isolates the genetic variant that may help determine which patients will respond to acamprosate, making them likely candidates for successful treatment.<\/p>\n “This association finding is a first step towards development of a pharmacogenetic test allowing physicians to choose appropriate treatment for specific subgroups of alcohol-dependent patients,” says Victor Karpyak, M.D., Ph.D., lead author of the article, in a news release. “We believe that individualized treatment selection will eliminate the need for trial-and-error approaches and improve treatment efficacy in patients with alcohol-use disorders.”<\/p>\n","protected":false},"excerpt":{"rendered":" Researchers from the Mayo Clinic and their collaborators have released a new study identifying genetic markers that pinpoint which people may benefit most from administration of the drug acamprosate as treatment for alcoholism. While acamprosate is not a new AUD … Continued<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_links_to":"","_links_to_target":""},"categories":[17],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/pgdf.org\/wp-json\/wp\/v2\/posts\/871"}],"collection":[{"href":"https:\/\/pgdf.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pgdf.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pgdf.org\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pgdf.org\/wp-json\/wp\/v2\/comments?post=871"}],"version-history":[{"count":6,"href":"https:\/\/pgdf.org\/wp-json\/wp\/v2\/posts\/871\/revisions"}],"predecessor-version":[{"id":1004,"href":"https:\/\/pgdf.org\/wp-json\/wp\/v2\/posts\/871\/revisions\/1004"}],"wp:attachment":[{"href":"https:\/\/pgdf.org\/wp-json\/wp\/v2\/media?parent=871"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pgdf.org\/wp-json\/wp\/v2\/categories?post=871"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pgdf.org\/wp-json\/wp\/v2\/tags?post=871"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}